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Thursday, August 25, 2011
10:00 AM - 11:30 AM
CNLS Conference Room (TA-3, Bldg 1690)

Seminar

Theory and Simulation of Lipid Bilayers Including the Effects of Shape, Thickness, and Molecular Orientation

Max Watson
University of California, Santa Barbara

We present a unified continuum-level model for bilayer energetics that includes the effects of bending, compression, lipid orientation (tilting relative to the monolayer surface normal), and microscopic noise (protrusions). Expressions for the thermal fluctuation amplitudes of several physical quantities are derived. These predictions are shown to be in good agreement with molecular simulations of the fluid phase, gel phase, and liquid ordered phase lipids+cholesterol). Applications to deformations due to transmembrane proteins are also discussed.

Host: Paul Welch, T-4: PHYS OF CONDENSED MATTER & COMPLEX SYSTEMS