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Tuesday, November 07, 2017
1:00 PM - 2:00 PM
CNLS Conference Room (TA-3, Bldg 1690)

Seminar

The Foundation for Successful AI-driven Drug Discovery Approach

Tudor Oprea
The University of New Mexico

1. "Illuminating the Druggable Genome", an NIH project focused on accurate data wrangling, processing and analytics for target discovery. IDG shows that there is a knowledge deficit with respect to 2 out of 5 human proteins (see also this NRDD poster, http://www.nature.com/nrd/posters/druggablegenome/index.html). IDG data is available at https://pharos.nih.gov/idg/index 2. DrugCentral is an on-line compendium for drugs and drug targets, which can serve as basis for understanding the molecular basis of therapeutic action. Available at http://drugcentral.org/ 3. The 3 pillars of AI-enabled drug discovery are: drugs, proteins and diseases. We will discuss some efforts in target prioritization for drug discovery based on systemic data integration.

Host: Angel Garcia